Our Research Results

Abstract presentations at International Meetings

  1. Genome-wide association study identifies novel loci associated with baseline renal function and the rate of decline in renal function among Chinese patients with T2DM. Presented at the Scientific Sessions of the American Diabetes Association, New Orleans, USA, June 2016.
     
  2. Power Estimation and Sample Size Determination for Replication Studies of Genome-Wide Association Studies. Presented at the 14th Asia Pacific Bioinformatics Conference (APBC'16), January 2016.
     
  3. Genome wide association study identifies novel loci associated with coronary heart disease in type 2 diabetes. Presented at the World Diabetes Congress, Vancouver, Canada, December 2015.
     
  4. C-Reactive Protein Exacerbates Diabetic Kidney Fibrosis by Enhancing CD32-Smad3-mTOR Signaling in Human CRP-Tg/db/db Mice. Presented at the 1st International Congress of Chinese Nephrology, December 2015.
     
  5. Deletion of Smad3 Prevents Renal Fibrosis and Inflammation in Type 2 Diabetes (Young investigator award). Presented at the 1st International Congress of Chinese Nephrology, Hong Kong, December 2015.
     
  6. A Novel Therapy for Type-2 Diabetic Nephropathy by Targeting Smad3-dependent lncRNA_5318. Presented at the 1st International Congress of Chinese Nephrology, Hong Kong, December 2015.
     
  7. C-Reactive Protein Promotes renal fibrosis in Type 2 Diabetes via CD32-Smad3-mTOR Signaling pathway In Human CRP-Tg/db/db Mice. Presented at the The ASN Kidney Week 2015 Annual Meeting, San Diego, CA, USA, November 2015.
     
  8. Interactome-transcriptome analysis discovers Type 2 Diabetes signatures complementary to GWAS Loci. Presented at the Human Genome Variation and Complex Genome Analysis (HGV 2015), San Francisco, USA, November 2015.
     
  9. Platelet-derived growth factor AA mediates bone morphogenic protein-4 signaling in endothelial dysfunction. Presented at the EMBO meeting, Birmingham, UK, September 2015
     
  10. Ma RC, So WY, Tam CH, Jiang GZ, Luk AO, Lee HM, Lim KP, Wang X, Kong AP, Ng AC, Fan X, Lok S, Chan TF, Yip K, Tang N, Tsui S, Yu W, Tomlinson BT, Lan HY, Huang Y, Szeto CC, Chan JC, on behalf of the TRANSCEND Consortium. Genome wide association study identifies novel loci associated with coronary heart disease in type 2 diabetes. Abstract accepted for presentation at the World Diabetes Congress, Vancouver, 30 Nov-4 Dec 2015.
     
  11. Li JW, Lee HM, Yip KY, Ma RC, Chan JC, Chan TF. Interactome-transcriptome analysis discovers Type 2 diabetes signatures complementary to GWAS loci. Abstract submitted and accepted for presentation at the 16th International Meeting on Human Genome Variation and Complex Genome Analysis, San Francisco, USA, 11-13 Nov, 2015.
     
  12. Xu B, You YK, Sun SF, Huang XR, Liu HF, Ma RC, Lan HY: Deletion of Smad3 Prevents Renal Fibrosis and Inflammation in Type 2 Diabetes. Abstract to be presented at The 1st International Congress of Chinese Nephrology (Hong Kong, 13-15/12/2015).
     
  13. Si F. Sun, Xiao R Huang, Min Feng, Patrick Tang, Ronald CW Ma, Hui Y Lan: A Novel Therapy for Type-2 Diabetic Nephropathy by Targeting Smad3-dependent lncRNA_5318. Abstract accepted for presentation at The 1st International Congress of Chinese Nephrology ( Hong Kong, 13-15/12/2015)
     
  14. Hui Yao Lan, Yong ke You, Bihua Xu, Xiao Ru Huang. C-Reactive Protein Promotes renal fibrosis in Type 2 Diabetes via CD32-Smad3-mTOR Signaling pathway In Human CRP-Tg/db/db Mice. The ASN Kidney Week 2015 Annual Meeting, November 3-8 in San Diego, CA (selected as Oral presentation)
     
  15. Jiang GZ, Tam CH, Wang Y, Lee HM, Fan X, Kong A, Chow CC, So WY, Chan JC, Ma RC. Progression to insulin for patients initiated on metformin, sulphonylurea and metformin-sulphonylurea therapy: an analysis from the Hong Kong Diabetes Registry. Abstract presented at the European Diabetes Epidemiology Group Meeting, Chantilly, France, 25-28 April, 2015.
     
  16. Ma RC, Tam CH, Jiang G, Wang Y, Lee HM, Lim C, So WY, Chan JC. Predicting insulin use in Chinese patients with type 2 diabetes using clinical and genetic information. Abstract presented at the Human Genome Meeting, Kuala Lumpur, 14-17 March, 2015.
     
  17. Ma RC, So WY, Tam CH, Luk AO, Lee HM, Lim KP, Wang X, Ng AC, Fan X, Lok S, Chan TF, Yip K, Tang N, Tsui S, Yu W, Tomlinson BT, Huang Y, Lan HY, Szeto CC, Chan JC, on behalf of the TRANSCEND Consortium. Genome-wide association study identifies novel loci associated with end-stage renal disease in Chinese subjects with type 2 diabetes. Abstract presented at the 97th Annual Meeting of the Endocrine Society, San Diego, March 5-8, 2015 and the Rachmiel Levine Symposium (San Diego, March 2015).
     
  18. Jiang GZ, Luk AO, Tam CH, Wang Y, Lee HM, Fan X, Kong AP, Chow CC, So WY, Chan JC, Ma RC. Progression to treatment failure among Chinese patients with type 2 diabetes initiated on metformin versus sulphonylurea monotherapy- The Hong Kong Diabetes Registry. Abstract presented at the International Diabetes Federation Western Pacific Regional Conference/6th Asian Association for the Study of Diabetes Meeting, November 2014, Singapore.
     
  19. Ma RC, Ho JS, Wang Y, Tam CH, Lam VK, Jiang G, Lee HM, Lau SH, Luk AO, Tsui SK, Tong PC, Chow CC, Szeto CC, Ng MC, So WY, Chan JC. Genome-wide association study identifies novel variants associated with incident kidney disease in Chinese. Abstract presented at the European Association for the Study of Diabetes, September 2014, Vienna, Austria